Maria Sharapova has withdrawn from the WTA Rogers Open in Montreal with a shoulder injury which could jeopardise her Olympics and US Open participation.
The world number three will have an MRI scan on Thursday after struggling with pain in her second-round 7-5 5-7 6-2 win over Poland's Marta Domachowska.
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Elsewhere, top seed Ana Ivanovic stuttered to a win over Petra Kvitova.
Playing with a swollen thumb, the world number one advanced to the third round with a 6-3 4-6 6-3 win over the Czech 18-year-old.
The top seed and 2006 champion, who had a first-round bye, overcame nine double faults and the loss of her serve five times against a player who beat Venus Williams in Memphis earlier this year.
Serb compatriot and world number two Jelena Jankovic cruised through with a 6-0 6-4 win over Aleksandra Wozniak of Canada.
Ivanovic, making her first match since crashing out of Wimbledon in the third round, must finish higher than Jankovic and Sharapova in Montreal to cling on to the world number one ranking she has held since winning the French Open in early June.
Sharapova needed a trainer to look at her right shoulder in the middle of the second set against Domachowska in a match which lasted nearly three hours and was strewn with double faults, the Russian making 17 in total.
She has struggled this year with a shoulder injury that forced her, ahead of the French Open, to withdraw from the Italian Open in June - though she did not appear 100% comfortable in Paris.
Sharapova also withdrew from the Sony Ericsson Open in Miami in March, again citing a shoulder problem.
Ivanovic, who refused to use her swollen thumb as an excuse for her poor display, will play Tamira Paszek of Austria in the third round after she beat Melinda Czink of Hungary 6-4 7-5.
Sharapova was set to meet Japanese veteran Ai Sugiyama while Jankovic will face another Canadian in the shape of Stephanie Dubois, who upset number 13 seed Maria Kirilenko of Russia 6-2 2-6 7-6 (7-4).
Also advancing from the second round were Russian seeds Anna Chakvetadze, Dinara Safina and Nadia Petrova, along with 15-year-old Michelle Larcher de Brito.
(BBC)
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