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Stem cell hope for osteoarthritis ... Madonna has announced that she will launch her 27-date world tour in Cardiff on 23 August.
The Sticky and Sweet tour will start at the Millennium Stadium, winding up in Miami on 26 November.
Tickets go on sale from 0900 BST 16 May with prices for the Cardiff show, starting at Ј55.
The tour will stop in major cities across Europe including London and Paris, as well as cities in the US.
Her last tour was in 2006 and concert organisers said more than 1.3m people went to her shows at venues across the world.
It made her the highest-grossing concert tour by a female artist at the time.
Her recent album, Hard Candy, has debuted at number one at 27 countries so far including the US, UK, France, Germany, Japan and Australia, according to her record company.
The 49-year-old star is due to play BBC Radio 1's Big Weekend in Kent on Saturday.
(BBC)
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